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Sandhini Lockman


Revealing new ways to cure disorders

Sandhini Lockman’s research could unveil a neurological process nature has kept hidden from us, and if brought to light, it will reveal new ways to cure a variety of disorders.

She grew up in Winnipeg wanting to be doctor, reading books about bacteria and bones. But when she arrived at the U of M on a scholarship, she discovered her true passion was biochemistry, which is good news for all of us.

Lockman, a master’s student and 3MT finalist working in the laboratory of U of M’s Mojgan Rastegar, studies Rett syndrome (RTT), a neurodevelopmental condition. Caused by a rare mutation on the X chromosome, it typically kills boys within their first year. For baby girls, after about six months, it begins to slowly and ceaselessly reverse their development, robbing them of the skills their parents only just proudly celebrated: their ability to crawl, walk, babble, see and use their hands. There is no cure, but that is where Lockman’s work comes in.

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